| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-09-25 |
| タイトル |
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タイトル |
Modulation of the cortical silent period elicited by single- and paired-pulse transcranial magnetic stimulation |
| 言語 |
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言語 |
eng |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Transcranial magnetic stimulation |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Motor evoked potential |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Cortical silent period |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Short-interval intracortical inhibition |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Intracortical facilitation |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Kojima, Sho
Onishi, Hideaki
Sugawara, Kazuhiro
Kirimoto, Hikari
Suzuki, Makoto
Tamaki, Hiroyuki
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background The cortical silent period (CSP) elicited by transcranial magnetic stimulation (TMS) is affected by changes in TMS intensity. Some studies have shown that CSP is shortened or prolonged by short- interval intracortical inhibition (SICI) and intracortical facilitation (ICF), Those studies, however, used different TMS intensities to adjust the amplitude of the motor evoked potential (MEP). Therefore, it is unclear whether changes in CSP duration are induced by changes in TMS intensities or by SICI and ICF. The purpose of this study was to confirm the effects of muscle contractions and stimulus intensities on MEP amplitude and the duration of CSP induced by single-pulse TMS and to clarify the effects of SICI and ICF on CSP duration. MEP evoked by TMS was detected from the right first dorsal interosseous muscle in 15 healthy subjects. First, MEP and CSP were induced by single-pulse TMS with an intensity of 100% active motor threshold (AMT) at four muscle contraction levels [10%, 30%, 50%, and 70% electromyogram (EMG)]. Next, MEP and CSP were induced by seven TMS intensities (100%, 110%, 120%, 130%, 140%, 150%, and 160% AMT) during muscle contraction of 10% EMG. Finally, SICI and ICF were recorded at the four muscle contraction levels (0%, 10%, 30%, and 50% EMG). Results MEP amplitudes increased with increases in muscle contraction and stimulus intensity. However, CSP duration did not differ at different muscle contraction levels and was prolonged with increases in stimulus intensity. CSP was shortened with SICI compared with CSP induced by single-pulse TMS and with ICF at all muscle contraction levels, whereas CSP duration was not significantly changed with ICF. Conclusions We confirmed that CSP duration is affected by TMS intensity but not by the muscle contraction level. This study demonstrated that CSP is shortened with SICI, but it is not altered with ICF. These results indicate that after SICI, CSP duration is affected by the activity of inhibitory intermediate neurons that are activated by the conditioning SICI stimulus. |
| 書誌情報 |
BMC Neuroscience
巻 14,
号 43,
p. 1-10,
発行日 2013-04
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| 出版者 |
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出版者 |
BioMed Central Ltd. |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1471-2202 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12035336 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
http://doi.org/10.1186/1471-2202-14-43 |
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関連名称 |
info:doi/10.1186/1471-2202-14-43 |
| 権利 |
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|
権利情報 |
Copyright © 2013 Kojima et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| 資源タイプ |
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内容記述タイプ |
Other |
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内容記述 |
論文(Article) |
| 資源タイプ・NII |
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Journal Article |
| 資源タイプ・DCMI |
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text |
| 異版である |
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関連タイプ |
isVersionOf |
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識別子タイプ |
URI |
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関連識別子 |
http://www.biomedcentral.com/1471-2202/14/43 |
063_kojima_s.pdf (669.9 kB)
