@article{oai:nsg.repo.nii.ac.jp:00004719, author = {Toda, Haruo}, issue = {1}, journal = {Niigata journal of health and welfare, 1346-8782}, month = {}, note = {application/pdf, 論文(Article), Heart rate variability (HRV) is an established measure for evaluating changes in human autonomic nervous functions, including reactions to mental stresses. In particular, the ratio of the low-frequency components (low-frequency (LF), 0.04–0.15 Hz) to the high-frequency components (HF, 0.15–0.40 Hz) in the R-R interval fluctuation (the LF/HF ratio) reflects the sympathetic tonus of the subject. This study introduces an easy-to-use R-R interval analyzer with a graphical user interface (GUI) for electrophysiological studies of HRV. The GUI framework and the analyzer itself are open source and the complete source code is freely accessible via the Internet, allowing their modification or customization by users. This application was tested in subjects under oral enquiries on the national examination which they were preparing for. Besides the low-cutoff frequency was low (0.08 Hz), more than 95% QRS complexes were automatically detected, indicating the usefulness of the application.}, pages = {55--66}, title = {An open-source R-R interval analyzer with a graphical user interface for electrophysiological studies}, volume = {18}, year = {2018} }