{"created":"2023-05-15T11:34:37.676739+00:00","id":5262,"links":{},"metadata":{"_buckets":{"deposit":"58c1590e-8487-49e3-a3aa-a17b5e3fa6dd"},"_deposit":{"created_by":11,"id":"5262","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"5262"},"status":"published"},"_oai":{"id":"oai:nsg.repo.nii.ac.jp:00005262","sets":["6:10:13"]},"author_link":["18595","18781","18621","19122","19123","19125","19012","19124","18624"],"control_number":"5262","item_19_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"2010","bibliographicPageStart":"2001","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Cerebral Cortex","bibliographic_titleLang":"en"}]}]},"item_19_description_16":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_19_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Two-point discrimination (2PD) test ref lects somatosensory spatial discrimination ability, but evidence on the relationship between 2PD and cortical gray matter (GM) volume is limited. This study aimed to analyze the relationship between cortical GM volume and 2PD threshold in young healthy individuals and to clarify the characteristics of brain structure ref lecting the individual differences in somatosensory function. 2PD was measured in 42 healthy (20 females) volunteers aged 20–32 years using a custom-made test system that can be controlled by a personal computer. The 2PD of the right index finger measured with this device has been confirmed to show good reproducibility. T1-weighted images were acquired using a 3-T magnetic resonance imaging scanner for voxel-based morphometry analysis. The mean 2PD threshold was 2.58 ± 0.54 mm. Whole-brain multiple regression analysis of the relationship between 2PD and GM volume showed that a lower 2PD threshold (i.e. better somatosensory function) significantly correlated with decreased GM volume from the middle temporal gyrus to the inferior parietal lobule (IPL) in the contralateral hemisphere. In conclusion, a lower GM volume in the middle temporal gyrus and IPL correlates with better somatosensory function. Thus, cortical GM volume may be a biomarker of somatosensory function.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_19_link_80":{"attribute_name":"PMCID","attribute_value_mlt":[{"subitem_link_text":"PMC9977372","subitem_link_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977372/"}]},"item_19_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press","subitem_publisher_language":"en"}]},"item_19_relation_12":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"35580840","subitem_relation_type_select":"PMID"}}]},"item_19_relation_13":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1093/cercor/bhac188","subitem_relation_type_select":"DOI"}}]},"item_19_rights_14":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permission@oup.com This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com","subitem_rights_language":"en"}]},"item_19_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1047-3211","subitem_source_identifier_type":"PISSN"}]},"item_19_text_47":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Journal Article"}]},"item_19_text_48":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_19_text_79":{"attribute_name":"ONLINE ISSN","attribute_value_mlt":[{"subitem_text_value":"1460-2199"}]},"item_19_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Onishi, Hideaki","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Nagasaka, Kazuaki","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Yokota, Hirotake","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Kojima, Sho","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ohno, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakurai, Noriko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kodama, Naoki","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Sato, Daisuke","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Otsuru, Naofumi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-07"}],"displaytype":"detail","filename":"002_onishi_h.pdf","filesize":[{"value":"920.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"002_onishi_h","url":"https://nsg.repo.nii.ac.jp/record/5262/files/002_onishi_h.pdf"},"version_id":"bd11c234-f3ad-4912-a404-1d8412e3d4b5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gray matter","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"inferior parietal lobe","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"middle temporal gyrus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"2-point discrimination","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"VBM","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association between somatosensory sensitivity and regional gray matter volume in healthy young volunteers : a voxel-based morphometry study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association between somatosensory sensitivity and regional gray matter volume in healthy young volunteers : a voxel-based morphometry study","subitem_title_language":"en"}]},"item_type_id":"19","owner":"11","path":["13"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-07"},"publish_date":"2023-03-07","publish_status":"0","recid":"5262","relation_version_is_last":true,"title":["Association between somatosensory sensitivity and regional gray matter volume in healthy young volunteers : a voxel-based morphometry study"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-08-08T01:04:51.568687+00:00"}