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Myocilin from COS-1 cells binds specifically to NIH3T3 cells
https://nsg.repo.nii.ac.jp/records/3856
https://nsg.repo.nii.ac.jp/records/3856e639aa18-8847-4e24-99b5-ab05e2794317
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
042_053e0901.pdf (474.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2011-05-25 | |||||||
| タイトル | ||||||||
| タイトル | Myocilin from COS-1 cells binds specifically to NIH3T3 cells | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Myocilin | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Glaucoma | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
Minami, Masayoshi
× Minami, Masayoshi
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Myocilin gene is directly linked to the most common form of glaucoma. The gene product is secreted into aqueous humor and is thought to be involved in the regulation of intraocular pressure. Most of the mutant myocilin proteins accumulate in cultured cells and are not secreted. In this study, through staining experiments of various cell lines, we demonstrated that secreted myocilin could bind to a particular cell surface to exert its function. Myocilin secreted by COS-1 cells was able to bind specifically to the surface of NIH3T3 cells. The binding of myocilin was dependent on the cell density. These results suggest that myocilin recognizes a specific cell and exerts its effect upon binding to the cell surface. | |||||||
| 書誌情報 |
Niigata journal of health and welfare 巻 9, 号 1, p. 42-53, 発行日 2009 |
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| 出版者 | ||||||||
| 出版者 | Niigata Society of Health and Welfare | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 1346-8782 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA11614542 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 資源タイプ | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 論文(Article) | |||||||
| 資源タイプ・NII | ||||||||
| Journal Article | ||||||||
| 資源タイプ・DCMI | ||||||||
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